Everything began with God. He is the Alpha. This is the solid foundation of truth upon which all else rests.
Man has often doubted and questioned this truth. Yet he has never been able to come up with anything simpler than the fact that everything began with God. Man, in his futile attempt to prove that there was a different kind of beginning has only come up with theories and probabilities.
But the Bible is certain. It deals with certainties. And we understand these certainties by faith.
The significance of all this in your life is the lesson that you should begin with God whatever be that you begin. Then God will watch over what you have begun and will ensure that it will be completed too.